Since the universal acknowledgment of antigenecity based on the rapid development of immunochemistry and immunopathology, much has been done about the allergic disease.
Skin test for the allergic conditions (e.g. Hay Fever, Bronchial Asthma), new allergen and its preparations were already developed in the 1920’ s. In the otolaryngologic field, physicians experienced not a few cases of nasal allergy with symptoms of persistent nasal obstruction, watery rhinorrhea, sneezing and rhinoscopic findings of.pale edematous swollen turbinate. But there are many difficulties in the definite diagnosis of nasal allergy without the objective diagnosis of nasal allergy positive findings of skirr test and eosinophil count and provocation test.
In the present study, skin test with 6 various antigen (house dust, wool, ragweed, candida, aspergillus and cedar), provocation test with antigenic disc and eosinophil count in nasal secretion to the 32 patient of allergic rhinitis, etc. have been carried out. The results are as follows:
1. The positive responses to allergic skin test seems to be valid, as to response is found- in control group.
2. The most frequent antigen was H.D. (50%), and next was candida (34.6%), regweed. (15.4%), aspergillus and cedar in order, but no response to the wool.
3. The positive reactions to allergenic provocation test was observed in 58.4% of the cases of positive skin test -and 33. 3% of the negative ones.
4. Despite no rsponse to the skin and provocation test, about 40% of subjects revealed eosinophilia in nasal secretion which seems to be due to unidentified antigen.
5. The most common seasonal prevalancy is spring and winter, which afford the possibilities that one of the most possible causative factors of allergic rhinitis in Korea is cold and pollen.
6. If the above three responses (skin test, provocationn test, and eosinophil count) in allergic rhinitis prove positive, its diagnostic value will be recognized.
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